Detection of IgG against the Foot-and-Mouth Disease Virus (FMDV) non- structural polyprotein 3ABC in cattle and sheep

نویسندگان

  • R. M. Armstrong
  • Z. Zhang
  • N. Aggarwal
  • P. A. Hamblin
  • S. J. Cox
چکیده

Results from in-house assays to detect cattle or sheep IgG against 3ABC were compared with those from a commercially available test kit in naïve or infected animals, and those first vaccinated then challenged with foot-and-mouth disease virus (FMDV) type O. Bovine IgG1 could be detected 7 days post infection or challenge (dpi or dpc) using the in-house method (3 days after neutralising antibodies) but only after 10 days using the kit. Ovine IgG1+2 was detected by the in-house method as early as 10-12 dpc (an average 4 days after neutralising responses) and 2.5 days before the commercial method.

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تاریخ انتشار 2003